Published Data Registry

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TitleAuthorsJournalPublication year
DOI
PMID
CSF and venous blood flow from childhood to adulthood studied by real-time phase-contrast MRI(Open Access) Sahoo P, Kollmeier JM, (...), Dreha-Kulaczewski SChilds Nervous System2024
Folate receptor α deficiency – Myelin‐sensitive MRI as a reliable biomarker to monitor the efficacy and long‐term outcome of a new therapeutic approach(Open Access) Dreha‐Kulaczewski S, Sahoo P, (...), Gärtner JJournal of Inherited Metabolic Disease2024
L-Lactate Treatment at 24 h and 48 h after Acute Experimental Stroke Is Neuroprotective via Activation of the L-Lactate Receptor HCA1(Open Access) Geiseler SJ, Hadzic A, (...), Morland CInternational Journal of Molecular Sciences2024
Long term follow-up in GAMT deficiency – Correlation of therapy regimen, biochemical and in vivo brain proton MR spectroscopy data(Open Access) Marten LM, Krätzner R, (...), Dreha-Kulaczewski SMolecular Genetics and Metabolism Reports2024
Direct neuronal reprogramming of NDUFS4 patient cells identifies the unfolded protein response as a novel general reprogramming hurdleSonsalla G, Malpartida AB, (...), Masserdotti GNeuron2024
IntelliR: A comprehensive and standardized pipeline for automated profiling of higher cognition in mice(Open Access) Gastaldi VD, Hindermann M, (...), Ehrenreich HbioRxiv2024
Validating a minipig model of reversible cerebral demyelination using human diagnostic modalities and electron microscopy(Open Access) Ancău M, Tanti GK, (...), Hemmer BeBioMedicine2024
In-situ architecture of the human prohibitin complex(Open Access) Lange F, Ratz M, (...), Jakobs SbioRxiv2024
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4(Open Access) Afzali AM, Nirschl L, (...), Korn TNature2024
Plasma Lipidomic Profiling Using Mass Spectrometry for Multiple Sclerosis Diagnosis and Disease Activity Stratification (LipidMS)(Open Access) Lattau SSJ, Borsch L, (...), Fitzner DInternational Journal of Molecular Sciences2024
Differential Role of Factor XIII in Acute Myocardial Infarction and Ischemic Stroke(Open Access) Traub J, Weber MS, Frey ABiomedicines2024
The astrocyte-produced growth factor HB-EGF limits autoimmune CNS pathology(Open Access) Linnerbauer M, Lößlein L, (...), Rothhammer VNature Immunology2024
Risk factors and outcomes after interruption of sedation in subarachnoid hemorrhage (ROUTINE-SAH) -a retrospective cohort study(Open Access) Schmidbauer M, Läufer S, Maskos A, Dimitriadis KFrontiers in Neurology2024
Polyglutamylation of microtubules drives neuronal remodeling(Open Access) Gavoci A, Zhiti A, (...), Brill MSbioRxiv2024
Gut–Brain Interactions and Their Impact on Astrocytes in the Context of Multiple Sclerosis and Beyond(Open Access) Zißler J, Rothhammer V, Linnerbauer MCells2024
Synaptogenic gene therapy with FGF22 improves circuit plasticity and functional recovery following spinal cord injury(Open Access) Aljović A, Jacobi A, (...), Bareyre FMEMBO Molecular Medicine2023
Targeting B Cells and Microglia in Multiple Sclerosis With Bruton Tyrosine Kinase InhibitorsDybowski S, Torke S, Weber MSJAMA Neurology2023
Drug screening identifies tazarotene and bexarotene as therapeutic agents in multiple sulfatase deficiency(Open Access) Schlotawa L, Tyka K, (...), Gärtner JEMBO Molecular Medicine2023
Membrane lipid remodeling modulates γ-secretase processivity(Open Access) Dawkins E, Derks RJ, (...), Steiner HJournal of Biological Chemistry2023
Antibodies Against Glutamic Acid Decarboxylase 65 Are Locally Produced in the CSF and Arise During Affinity Maturation(Open Access) Biljecki M, Eisenhut K, (...), Thaler FSNeurology-Neuroimmunology & Neuroinflammation2023
Exploiting moderate hypoxia to benefit patients with brain disease: Molecular mechanisms and translational research in progress(Open Access) Ehrenreich H, Gassmann M, (...), Miskowiak KNeuroprotection2023
Shared inflammatory glial cell signature after brain injury, revealed by spatial, temporal and cell-type-specific profiling of the murine cerebral cortex(Open Access) Koupourtidou C, Schwarz V, (...), Ninkovic JbioRxiv2023
Myelination generates aberrant ultrastructure that is resolved by microglia.Djannatian M, Radha S, (...), Simons MJournal of Cell Biology2023
Remyelination by surviving oligodendrocytes is inefficient in the inflamed mammalian cortex.Mezydlo A, Treiber N, (...), Kerschensteiner MNeuron2023
Neural dynamics and architecture of the heading direction circuit in zebrafish.(Open Access) Petrucco L, Lavian H, Wu YK, Svara F, Štih V, Portugues RNature neuroscience2023
2-Methoxyestradiol-3,17-O,O-bis-sulfamate inhibits store-operated Ca(2+) entry in T lymphocytes and prevents experimental autoimmune encephalomyelitis.Hosang L, Löhndorf A, (...), Flügel ABiochimica et Biophysica Acta-Molecular Cell Research2023
Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease(Open Access) Depp C, Sun T, (...), Nave KNature2023
Ex vivo immunocapture and functional characterization of cell-type-specific mitochondria using MitoTag micede Mello NP, Fecher C, Pastor AM, Perocchi F, Misgeld TNature Protocols2023
Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease(Open Access) Schäffner E, Bosch-Queralt M, (...), Stassart RMNature Neuroscience2023
Tipping points in neurodegeneration(Open Access) Simons M, Levin J, Dichgans MNeuron2023
Spatial Transcriptomics-correlated Electron Microscopy maps transcriptional and ultrastructural responses to brain injury(Open Access) Androvic P, Schifferer M, (...), Gokce ONature Communications2023
Visualizing the activation of encephalitogenic T cells in the ileal lamina propria by in vivo two-photon imaging(Open Access) Bauer IJ, Fang P, (...), Kawakami NProceedings of the National Academy of Sciences of the United States of America2023
Immune-mediated denervation of the pineal gland underlies sleep disturbance in cardiac diseaseZiegler KA, Ahles A, (...), Engelhardt SScience2023
Regulation of the programmed cell death protein 1/programmed cell death ligand 1axis in relapsing-remitting multiple sclerosisTsaktanis T, Linnerbauer M, (...), Rothhammer VBrain Communications2023
Erythropoietin re-wires cognition-associated transcriptional networks(Open Access) Singh M, Zhao Y, (...), Ehrenreich HNature Communications2023
Expanding the function of oligodendrocytes to brain energy metabolismNave K, Asadollahi E, Sasmita ACurrent Opinion in Neurobiology2023
Fibroblast growth factor 9 (FGF9) mediated neurodegeneration: implications for progressive multiple sclerosis?(Open Access) Thümmler K, Wrzos C, (...), Linington CNeuropathology and Applied Neurobiology2023
PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation(Open Access) Linnerbauer M, Beyer T, (...), Rothhammer VNature Communications2023
A genome-wide in vivo CRISPR screen identifies essential regulators of T cell migration to the CNS in a multiple sclerosis model(Open Access) Kendirli A, de la Rosa C, (...), Kawakami NNature Neuroscience2023
Targeting the TCA cycle can ameliorate widespread axonal energy deficiency in neuroinflammatory lesions(Open Access) Tai Y, Engels D, (...), Misgeld TNature Metabolism2023
Early Neuroaxonal Damage in Neurologic Disorders Associated With GAD65 Antibodies(Open Access) Eisenhut K, Faber J, (...), Thaler FSNeurology-Neuroimmunology & Neuroinflammation2023
Sekundärprophylaxe des ischämischen Schlaganfalls(Open Access) Schmidbauer M, Wischmann J, Dimitriadis K, Kellert LInnere Medizin2023
Injury-specific factors in the cerebrospinal fluid regulate astrocyte plasticity in the human brain(Open Access) Sirko S, Schichor C, (...), Götz MNature Medicine2023
Oligodendrocytes and neurons contribute to amyloid-β deposition in Alzheimer's disease(Open Access) Sasmita AO, Depp C, (...), Nave KbioRxiv2023
Characteristics, Prevalence, and Clinical Relevance of Juxtacortical Paramagnetic Rims in Patients With Multiple SclerosisGalbusera R, Bahn E, (...), Granziera CNeurology2023
An Animal Model for Chronic Meningeal Inflammation and Inflammatory Demyelination of the Cerebral Cortex(Open Access) Enz LS, Winkler A, (...), Schaeren-Wiemers NInternational Journal of Molecular Sciences2023
A fluorescence microscopy-based protocol for volumetric measurement of lysolecithin lesion-associated de- and re-myelination in mouse brain(Open Access) Bosch-Queralt M, Tiwari V, Damkou A, Vaculčiaková L, Alexopoulos I, Simons MSTAR Protocols2022
The lung microbiome regulates brain autoimmunityHosang L, Canals RC, (...), Odoardi FNature2022
A new form of axonal pathology in a spinal model of neuromyelitis optica(Open Access) Herwerth M, Kenet S, (...), Misgeld TBrain2022
Myelin lipids as nervous system energy reserves(Open Access) Asadollahi E, Trevisiol A, (...), Nave KbioRxiv2022
Innate Immune Pathways Promote Oligodendrocyte Progenitor Cell Recruitment to the Injury Site in Adult Zebrafish Brain(Open Access) Sanchez-Gonzalez R, Koupourtidou C, (...), Ninkovic JCells2022
Dynamics of Retinal Vessel Loss After Acute Optic Neuritis in Patients With Relapsing Multiple Sclerosis(Open Access) Aly L, Noll C, (...), Knier BNeurology-Neuroimmunology & Neuroinflammation2022
Size‐Selective Transfer of Lipid Nanoparticle‐Based Drug Carriers Across the Blood Brain Barrier Via Vascular Occlusions Following Traumatic Brain Injury(Open Access) Khalin I, Adarsh N, (...), Plesnila NSmall2022
Tissue-resident memory CD8+ T cells cooperate with CD4+ T cells to drive compartmentalized immunopathology in the CNSVincenti I, Page N, (...), Merkler DScience Translational Medicine2022
Introducing the brain erythropoietin circle to explain adaptive brain hardware upgrade and improved performance(Open Access) Ehrenreich H, Garcia-Agudo LF, Steixner-Kumar AA, Wilke JBH, Butt UJMolecular Psychiatry2022
Molecular Signature of Astrocytes for Gene Delivery by the Synthetic Adeno‐Associated Viral Vector rAAV9P1(Open Access) Bauer A, Puglisi M, (...), Brack‐Werner RAdvanced Science2022
Intranasal delivery of a small-molecule ErbB inhibitor promotes recovery from acute and late-stage CNS inflammation(Open Access) Linnerbauer M, Lößlein L, (...), Rothhammer VJCI Insight2022
Selective plasticity of callosal neurons in the adult contralesional cortex following murine traumatic brain injury(Open Access) Empl L, Chovsepian A, (...), Bareyre FMNature Communications2022
CNS Treg cells have alternative functions but run on conventional fuel(Open Access) Korn TNature Immunology2022
Ly6D+Siglec-H+ precursors contribute to conventional dendritic cells via a Zbtb46+Ly6D+ intermediary stage(Open Access) Lutz K, Musumeci A, (...), Krug ABNature Communications2022
Distinct roles of the meningeal layers in CNS autoimmunity(Open Access) Merlini A, Haberl M, (...), Odoardi FNature Neuroscience2022
P2R Inhibitors Prevent Antibody-Mediated Complement Activation in an Animal Model of Neuromyelitis Optica(Open Access) Kalluri SR, Srivastava R, (...), Herwerth MNeurotherapeutics2022
IL-24 intrinsically regulates Th17 cell pathogenicity in mice(Open Access) Sie C, Kant R, (...), Korn TJournal of Experimental Medicine2022
Autoantibodies against NMDAR subunit NR1 disappear from blood upon anesthesia(Open Access) Teller J, Jung C, (...), Ehrenreich HBrain, Behavior, & Immunity - Health2022
DNA-PAINT MINFLUX nanoscopy(Open Access) Ostersehlt LM, Jans DC, (...), Jakobs SNature Methods2022
Ketogenic diet uncovers differential metabolic plasticity of brain cells(Open Access) Düking T, Spieth L, (...), Saher GScience Advances2022
For decades against the mainstream – from erythropoietin and hypoxia as novel treatment strategies to deep phenotyping in neuropsychiatric disordersEhrenreich HPsychiatry Research2022
Ganglioside lipidomics of central nervous system myelination using direct infusion shotgun mass spectrometry(Open Access) Arends M, Weber M, (...), Simons MiScience2022
CD8+ T cells induce interferon-responsive oligodendrocytes and microglia in white matter aging(Open Access) Kaya T, Mattugini N, (...), Simons MNature Neuroscience2022
CNS remyelination and inflammation: From basic mechanisms to therapeutic opportunities(Open Access) Franklin RJ, Simons MNeuron2022
Factors predisposing to humoral autoimmunity against brain-antigens in health and disease Analysis of 49 autoantibodies in over 7000 subjects(Open Access) Daguano Gastaldi V, Bh Wilke J, (...), Ehrenreich HBrain, Behavior, and Immunity2022
A deep learning-based toolbox for Automated Limb Motion Analysis (ALMA) in murine models of neurological disorders(Open Access) Aljovic A, Zhao S, (...), Bareyre FMCommunications Biology2022
Isolated catatonia-like executive dysfunction in mice with forebrain-specific loss of myelin integrity(Open Access) Arinrad S, Depp C, (...), Nave KbioRxiv2022
TDP-43 condensates and lipid droplets regulate the reactivity of microglia and regeneration after traumatic brain injuryZambusi A, Novoselc KT, (...), Ninkovic JNature Neuroscience2022
Cognate microglia–T cell interactions shape the functional regulatory T cell pool in experimental autoimmune encephalomyelitis pathologyHaimon Z, Frumer GR, (...), Jung SNature Immunology2022
Plasticity of callosal neurons in the contralesional cortex following traumatic brain injury(Open Access) Bareyre F, Chovsepian A, Empl LNeural Regeneration Research2022
Postmortem quantitative MRI disentangles histological lesion types in multiple sclerosis(Open Access) Galbusera R, Bahn E, (...), Granziera CBrain Pathology2022
MCU controls melanoma progression through a redox‐controlled phenotype switch(Open Access) Stejerean‐Todoran I, Zimmermann K, (...), Bogeski IEMBO reports2022
Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain(Open Access) Liu T, Stephan T, (...), Chen ZProceedings of the National Academy of Sciences of the United States of America2022
T cells modulate the microglial response to brain ischemia(Open Access) Benakis C, Simats A, (...), Liesz AeLife2022
Coordinated neurostimulation promotes circuit rewiring and unlocks recovery after spinal cord injuryVan Steenbergen V, Burattini L, (...), Bareyre FMJournal of Experimental Medicine2022
Proteomics separates adult-type diffuse high-grade gliomas in metabolic subgroups independent of 1p/19q codeletion and across IDH mutational status(Open Access) Bader JM, Deigendesch N, Misch M, Mann M, Koch A, Meissner FCell Reports Medicine2022
Hemorrhagic lesion with detection of infected endothelial cells in human bornavirus encephalitis(Open Access) Liesche-Starnecker F, Schifferer M, (...), Finck TActa Neuropathologica2022
Reparative inflammation in multiple sclerosis(Open Access) Cantuti-Castelvetri L, Gokce O, Simons MSeminars in Immunology2022
Probing cell identity hierarchies by fate titration and collision during direct reprogramming(Open Access) Hersbach BA, Fischer DS, (...), Stricker SHMolecular Systems Biology2022
Brain injury environment critically influences the connectivity of transplanted neurons(Open Access) Grade S, Thomas J, (...), Götz MScience Advances2022
Cellular and Molecular Determinants of Retinal Cell FatePetridou E, Godinho LAnnual Review of Vision Science2022
Aquaporin-4 prevents exaggerated astrocytosis and structural damage in retinal inflammation(Open Access) Maisam Afzali A, Stüve L, (...), Korn TJournal of Molecular Medicine-JMM2022
The glioblastoma multiforme tumor site promotes the commitment of tumor-infiltrating lymphocytes to the TH17 lineage in humans(Open Access) Mitsdoerffer M, Aly L, (...), Korn TProceedings of the National Academy of Sciences of the United States of America2022
Oligodendrocyte precursor cells sculpt the visual system by regulating axonal remodeling(Open Access) Xiao Y, Petrucco L, Hoodless LJ, Portugues R, Czopka TNature Neuroscience2022
Neural labeling and manipulation by neonatal intraventricular viral injection in mice(Open Access) Wang M, Misgeld T, Brill MSSTAR Protocols2022
Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43(Open Access) Heo D, Ling JP, (...), Bergles DEeLife2022
White matter integrity in mice requires continuous myelin synthesis at the inner tongue(Open Access) Meschkat M, Steyer AM, (...), Möbius WNature Communications2022
Astrocyte-Derived Pleiotrophin Mitigates Late-Stage Autoimmune CNS Inflammation(Open Access) Linnerbauer M, Lößlein L, (...), Rothhammer VFrontiers in Immunology2022
Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain(Open Access) Liu T, Stephan T, (...), Chen ZbioRxiv2022
Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19(Open Access) Meinhardt J, Radke J, (...), Heppner FLNature Neuroscience2021
Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis.(Open Access) Berghoff SA, Spieth L, (...), Saher GNature Neuroscience2021
Phagocyte-mediated synapse removal in cortical neuroinflammation is promoted by local calcium accumulation(Open Access) Jafari M, Schumacher A, (...), Kerschensteiner MNature Neuroscience2021
Completion of neuronal remodeling prompts myelination along developing motor axon branchesWang M, Kleele T, (...), Brill MSJournal of Cell Biology2021
Myelin biogenesis is associated with pathological ultrastructure that is resolved by microglia during development(Open Access) Djannatian M, Weikert U, (...), Simons MbioRxiv2021
Post-injury immunosuppression and secondary infections are caused by an AIM2 inflammasome-driven signaling cascadeRoth S, Cao J, (...), Liesz AImmunity2021
Formation and immunomodulatory function of meningeal B-cell aggregates in progressive CNS autoimmunity(Open Access) Mitsdörffer M, Di Liberto G, (...), Korn TBrain2021
Proteomics reveals distinct mechanisms regulating the release of cytokines and alarmins during pyroptosis(Open Access) Phulphagar K, Kühn LI, (...), Meissner FCell Reports2021
CaMKIIα Expressing Neurons to Report Activity-Related Endogenous Hypoxia upon Motor-Cognitive Challenge(Open Access) Butt UJ, Hassouna I, (...), Ehrenreich HInternational Journal of Molecular Sciences2021
TSPO PET imaging of natalizumab-associated progressive multifocal leukoencephalopathyMahler C, Schumacher A, (...), Kerschensteiner MBrain2021
2-Methoxyestradiol and its derivatives inhibit store-operated Ca2+ entry in T cells: Identification of a new and potent inhibitor.(Open Access) Löhndorf A, Hosang L, (...), Guse AHBiochimica et Biophysica Acta-Molecular Cell Research2021
Blood-brain barrier resealing in neuromyelitis optica occurs independently of astrocyte regeneration.(Open Access) Winkler A, Wrzos C, (...), Stadelmann CJournal of Clinical Investigation2021
Diet-dependent regulation of TGFβ impairs reparative innate immune responses after demyelination.Bosch-Queralt M, Cantuti-Castelvetri L, (...), Simons MNature Metabolism2021
White matter aging drives microglial diversity.Safaiyan S, Besson-Girard S, (...), Simons MNeuron2021
Hippocampal neurons respond to brain activity with functional hypoxia.(Open Access) Butt UJ, Steixner-Kumar AA, (...), Ehrenreich HMolecular Psychiatry2021
Semaphorin 7A restricts serotonergic innervation and ensures recovery after spinal cord injury.(Open Access) Loy K, Fourneau J, Meng N, Denecke C, Locatelli G, Bareyre FMCellular and molecular life sciences : CMLS2021
The Positive Switching Fluorescent Protein Padron2 Enables Live-Cell Reversible Saturable Optical Linear Fluorescence Transitions (RESOLFT) Nanoscopy without Sequential Illumination Steps.(Open Access) Konen T, Stumpf D, (...), Jakobs SACS Nano2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapiesHeindl S, Ricci A, (...), Liesz AJournal of Experimental Medicine2021
Dissociation of microdissected mouse brain tissue for artifact free single-cell RNA sequencing(Open Access) Liu L, Besson-Girard S, (...), Gokce OSTAR Protocols2021
Concurrent axon and myelin destruction differentiates X‐linked adrenoleukodystrophy from multiple sclerosis(Open Access) Bergner CG, Genc N, (...), Stadelmann CGlia2021
Chemogenetic approaches to unravel circuit wiring and related behavior after spinal cord injury(Open Access) Van Steenbergen V, Bareyre FMExperimental Neurology2021
Autoantibodies against NMDA receptor 1 modify rather than cause encephalitis(Open Access) Wilke JBH, Hindermann M, (...), Ehrenreich HMolecular Psychiatry2021
Brain erythropoietin fine-tunes a counterbalance between neurodifferentiation and microglia in the adult hippocampus(Open Access) Fernandez Garcia-Agudo L, Steixner-Kumar AA, (...), Ehrenreich HCell Reports2021
TREM2-dependent lipid droplet biogenesis in phagocytes is required for remyelinationGouna G, Klose C, (...), Simons MJournal of Experimental Medicine2021
Notch-mediated re-specification of neuronal identity during central nervous system development(Open Access) Engerer P, Petridou E, (...), Godinho LCurrent Biology2021
Repositioning TH cell polarization from single cytokines to complex helpTuzlak S, Dejean AS, (...), Becher BNature Immunology2021
Addressing the ‘hypoxia paradox’ in severe COVID-19: literature review and report of four cases treated with erythropoietin analogues(Open Access) Begemann M, Gross O, (...), Ehrenreich HMolecular Medicine2021
Proteomic and lipidomic profiling of demyelinating lesions identifies fatty acids as modulators in lesion recovery(Open Access) Penkert H, Bertrand A, (...), Simons MCell Reports2021
Río‐Hortega's drawings revisited with fluorescent protein defines a cytoplasm‐filled channel system of CNS myelin(Open Access) Edgar JM, McGowan E, (...), Boullerne AJournal of Anatomy2021
Optical coherence tomography angiography indicates subclinical retinal disease in neuromyelitis optica spectrum disorders(Open Access) Aly L, Strauß E, (...), Knier BMultiple Sclerosis Journal2021
Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy(Open Access) Kettwig M, Ternka K, (...), Gärtner JNature Communications2021
Role of IL-6 in the commitment of T cell subsets(Open Access) Korn T, Hiltensperger MCytokine2021
The TFAM-to-mtDNA ratio defines inner-cellular nucleoid populations with distinct activity levels(Open Access) Brüser C, Keller-Findeisen J, Jakobs SCell Reports2021
Coming to the Rescue: Regulatory T Cells for Promoting Recovery After Ischemic StrokeZhang Y, Liesz A, Li PStroke2021
Three-dimensional virtual histology of the human hippocampus based on phase-contrast computed tomography(Open Access) Eckermann M, Schmitzer B, (...), Salditt TProceedings of the National Academy of Sciences of the United States of America2021
A macrophage-T cell coculture model for severe tissue injury-induced T cell death(Open Access) Zhu J, Cao J, Liesz A, Roth SSTAR Protocols2021
NMDAR1 autoantibodies amplify behavioral phenotypes of genetic white matter inflammation: a mild encephalitis model with neuropsychiatric relevance(Open Access) Arinrad S, Wilke JBH, (...), Ehrenreich HMolecular Psychiatry2021
Amyloid-like aggregating proteins cause lysosomal defects in neurons via gain-of-function toxicity(Open Access) Riera-Tur I, Schäfer T, (...), Dudanova ILife Science Alliance2021
Skin and gut imprinted helper T cell subsets exhibit distinct functional phenotypes in central nervous system autoimmunity(Open Access) Hiltensperger M, Beltrán E, (...), Korn TNature Immunology2021
Niwaki Instead of Random Forests: Targeted Serial Sectioning Scanning Electron Microscopy With Reimaging Capabilities for Exploring Central Nervous System Cell Biology and Pathology(Open Access) Schifferer M, Snaidero N, Djannatian M, Kerschensteiner M, Misgeld TFrontiers in Neuroanatomy2021
Interleukin-23 receptor expressing γδ T cells locally promote early atherosclerotic lesion formation and plaque necrosis in mice(Open Access) Gil-Pulido J, Amézaga N, (...), Zernecke ACardiovasc Res2021
Identification of covalent modifications regulating immune signaling complex composition and phenotype(Open Access) Frauenstein A, Ebner S, (...), Meissner FMolecular Systems Biology2021
The Aryl Hydrocarbon Receptor–Dependent TGF-α/VEGF-B Ratio Correlates With Disease Subtype and Prognosis in Multiple Sclerosis(Open Access) Cirac A, Tsaktanis T, (...), Rothhammer VNeurology-Neuroimmunology & Neuroinflammation2021
The Gut-Brain Axis in Inflammatory Bowel Disease - Current and Future Perspectives(Open Access) Günther C, Rothhammer V, Karow M, Neurath M, Winner BInternational Journal of Molecular Sciences2021
Semaphorin7A: its role in the control of serotonergic circuits and functional recovery following spinal cord injury(Open Access) Bareyre F, Fourneau JNeural Regeneration Research2021
Transthyretin Promotes Axon Growth via Regulation of Microtubule Dynamics and Tubulin Acetylation(Open Access) Eira J, Magalhães J, (...), Liz MAFrontiers in Cell and Developmental Biology2021
TUNAR lncRNA Encodes a Microprotein that Regulates Neural Differentiation and Neurite Formation by Modulating Calcium Dynamics(Open Access) Senís E, Esgleas M, (...), Abad MFrontiers in Cell and Developmental Biology2021
Correction: Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2(Open Access) Kempf J, Knelles K, (...), Masserdotti GCell Reports2021
Neuronal replacement: Concepts, achievements, and call for caution(Open Access) Götz M, Bocchi RCurrent Opinion in Neurobiology2021
The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells(Open Access) Wenzel J, Lampe J, (...), Schwaninger MNature Neuroscience2021
Urinary Levels of SARS-CoV-2 Nucleocapsid Protein Associate With Risk of AKI and COVID-19 Severity: A Single-Center Observational Study(Open Access) Tampe D, Hakroush S, (...), Tampe BFrontiers in Medicine2021
LC-MS Based Platform Simplifies Access to Metabolomics for Peroxisomal Disorders(Open Access) Klemp HG, Kettwig M, Streit F, Gärtner J, Rosewich H, Krätzner RMetabolites2021
Targeted metabolomics revealed changes in phospholipids during the development of neuroinflammation in Abcd1tm1Kds mice and X‐linked adrenoleukodystrophy patients(Open Access) Kettwig M, Klemp H, (...), Gärtner JJournal of Inherited Metabolic Disease2021
Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2(Open Access) Kempf J, Knelles K, (...), Masserdotti GCell Reports2021
Plasma lipidomics of monozygotic twins discordant for multiple sclerosis.(Open Access) Penkert H, Lauber C, (...), Simons MAnnals of Clinical and Translational Neurology2020
Multiple inducers and novel roles of autoantibodies against the obligatory NMDAR subunit NR1: a translational study from chronic life stress to brain injury.(Open Access) Pan H, Steixner-Kumar AA, (...), Ehrenreich HMolecular Psychiatry2020
Granulins Regulate Aging Kinetics in the Adult Zebrafish Telencephalon.(Open Access) Zambusi A, Pelin Burhan Ö, Di Giaimo R, Schmid B, Ninkovic JCells2020
Oligodendrocytes Provide Antioxidant Defense Function for Neurons by Secreting Ferritin Heavy Chain.Mukherjee C, Kling T, (...), Simons MCell Metabolism2020
Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS.(Open Access) LaClair KD, Zhou Q, (...), Edbauer DActa Neuropathologica2020
Formation of somatosensory detour circuits mediates functional recovery following dorsal column injury.(Open Access) Granier C, Schwarting J, (...), Bareyre FMScientific Reports2020
Myelin replacement triggered by single-cell demyelination in mouse cortex(Open Access) Snaidero N, Schifferer M, Mezydlo A, Zalc B, Kerschensteiner M, Misgeld TNature Communications2020
Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity.(Open Access) Cantuti-Castelvetri L, Ojha R, (...), Simons MScience2020
Multiscale ATUM-FIB Microscopy Enables Targeted Ultrastructural Analysis at Isotropic Resolution(Open Access) Kislinger G, Gnägi H, Kerschensteiner M, Simons M, Misgeld T, Schifferer MiScience2020
Cell-Type- and Brain-Region-Resolved Mouse Brain Lipidome.(Open Access) Fitzner D, Bader JM, (...), Simons MCell Reports2020
Pro-inflammatory activation following demyelination is required for myelin clearance and oligodendrogenesis.(Open Access) Cunha MI, Su M, (...), Simons MJournal of Experimental Medicine2020
Lack of astrocytes hinders parenchymal oligodendrocyte precursor cells from reaching a myelinating state in osmolyte-induced demyelination.(Open Access) Lohrberg M, Winkler A, (...), Barrantes-Freer AActa Neuropathologica Communications2020
Remyelination in multiple sclerosis: from basic science to clinical translation.(Open Access) Lubetzki C, Zalc B, Williams A, Stadelmann C, Stankoff BLancet Neurology2020
Molecular signature of slowly expanding lesions in progressive multiple sclerosis.(Open Access) Jäckle K, Zeis T, (...), Brück WBrain2020
Neural stem cells restore myelin in a demyelinating model of Pelizaeus-Merzbacher disease.(Open Access) Gruenenfelder FI, McLaughlin M, (...), Edgar JMBrain2020
ATUM-FIB microscopy for targeting and multiscale imaging of rare events in mouse cortex.(Open Access) Kislinger G, Gnägi H, Kerschensteiner M, Simons M, Misgeld T, Schifferer MSTAR Protocols2020
MOG-expressing teratoma followed by MOG-IgG-positive optic neuritis(Open Access) Wildemann B, Jarius S, Franz J, Ruprecht K, Reindl M, Stadelmann CActa Neuropathologica2020
Regulatory myeloid cells paralyze T cells through cell–cell transfer of the metabolite methylglyoxalBaumann T, Dunkel A, (...), Höchst BNature Immunology2020